Enhanced Edar Signalling Has Pleiotropic Effects on Craniofacial and Cutaneous Glands
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چکیده
منابع مشابه
Enhanced Edar Signalling Has Pleiotropic Effects on Craniofacial and Cutaneous Glands
The skin carries a number of appendages, including hair follicles and a range of glands, which develop under the influence of EDAR signalling. A gain of function allele of EDAR is found at high frequency in human populations of East Asia, with genetic evidence suggesting recent positive selection at this locus. The derived EDAR allele, estimated to have reached fixation more than 10,000 years a...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0007591